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Sometimes abnormal cells on the inner surface layer of the anus look like cancer cells but have not grown into any of the deeper layers. This is known as carcinoma in situ, (pronounced in sy-too), or cis. Anal cancer is an uncommon malignancy that starts in the anus-- the opening at the end of the rectum. The american society of clinical oncology estimates that 8,300 cases of anal cancer will be. Symptoms of anal cancer can include bleeding, bowel changes and severe itching (pruritus). These can also be symptoms for other conditions such as piles (haemorrhoids), but its important to see your doctor. Anal intraepithelial neoplasia (ain) anal intraepithelial neoplasia (ain) means there are abnormal cells in the lining of your anus. A pathologist looks at your cells under a microscope to check whether your anal cells look different to normal anal cells. At first, most people assume the bleeding is caused by hemorrhoids (painful, swollen veins in the anus and rectum that may bleed). Anal cancer is a type of cancer that forms in tissues of the anus. The anus is the opening of the rectum to the outside of the body and at the end of the gi tract.

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